https://blog.defectiv.es/en/tags/bio/Recent content in bio on Gaia Lab · BlogHugoen-GBWed, 23 Sep 2026 09:00:00 +0200https://blog.defectiv.es/en/posts/4400-complejos-de-proteinas-con-boltz-2/Tue, 22 Sep 2026 13:00:00 +0200https://blog.defectiv.es/en/posts/4400-complejos-de-proteinas-con-boltz-2/<p>Fourth instalment of <strong>Cluster X-ray</strong> and the line with the fewest jobs: fifteen. Also one of those that reserves the most GPU, because each job runs for days.</p> <h2 id="the-question">The question <a class="hanchor" href="#the-question" aria-label="Enlace a esta sección">#</a></h2> <p>Knowing whether two proteins interact, and how, is one of the central questions of structural biology: it explains signalling pathways, drug targets and the effect of mutations. Determining it experimentally costs months per pair. The line uses structure prediction to <strong>estimate, at the scale of thousands of pairs, the structure of the complex that two proteins form and the confidence that the binding is real.</strong></p>